{"id":2238,"date":"2022-07-26T18:02:08","date_gmt":"2022-07-26T09:02:08","guid":{"rendered":"http:\/\/shokubai.mediawars.ne.jp\/ja\/?post_type=products&#038;p=2238"},"modified":"2026-04-17T14:37:52","modified_gmt":"2026-04-17T05:37:52","slug":"biocompatible-polymer","status":"publish","type":"products","link":"https:\/\/www.shokubai.co.jp\/en\/products\/detail\/biocompatible-polymer\/","title":{"rendered":"Biocompatible Polymer &#8211; Nippon Shokubai&#8217;s Intermediate Water Polymer"},"content":{"rendered":"\n<div class=\"wp-block-my-gutenberg-my-block00 m_ancNav\"><ul class=\"anc_content\"><li><a href=\"#anc01\">Basic Information<\/a><\/li><li><a href=\"#anc02\">Features and Properties<\/a><\/li><li><a href=\"#anc03\">Examples of Applications<\/a><\/li><li><a href=\"#anc04\">Key Features and Properties<\/a><\/li><li><a href=\"#anc05\" title=\"\">Disclaimer<\/a><\/li><\/ul><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"anc01\">Basic Information<\/h2>\n\n\n\n<figure class=\"wp-block-flexible-table-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th><\/th><th colspan=\"2\"><strong>RX-6-GH-30<\/strong>\uff08in development\uff09<\/th><\/tr><\/thead><tbody><tr><th>Appearance<\/th><td colspan=\"2\">Colorless and transparent<\/td><\/tr><tr><th>Solid<\/th><td colspan=\"2\">30 \uff05\uff08aqueous\uff09<\/td><\/tr><tr><th>Viscosity<\/th><td colspan=\"2\">1000 \uff4dPas<\/td><\/tr><tr><th>Toxicity and Safety<\/th><td colspan=\"2\">Ames Test:\u3000Negative\uff085000\u03bcg\/plate\uff09 <br>Cytotoxicity: None (IC<sub>50 <\/sub>\uff1e\uff15000\u03bcg\/mL) <br>Skin Sensitization: Negative (Test concentration: 100% (v\/v); Positive rate: 0%)<\/td><\/tr><tr><th rowspan=\"6\">Wet adhesion (after curing)<\/th><td>polyester<\/td><td>excellent<\/td><\/tr><tr><td>nylon<\/td><td>good<\/td><\/tr><tr><td>vinyl cloride<\/td><td>excellent<\/td><\/tr><tr><td>sus\uff08304\uff09<\/td><td>poor<\/td><\/tr><tr><td>Al<\/td><td>poor<\/td><\/tr><tr><td>glass<\/td><td>good<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"anc02\">Features and Properties<\/h2>\n\n\n\n<ol start=\"1\" class=\"wp-block-list\">\n<li>Exhibits excellent biocompatibility due to a high content of intermediate water and a low proportion of non-freezing water.<\/li>\n\n\n\n<li>Forms coatings that combine hydrophilicity and water resistance when used in combination with crosslinking agents<\/li>\n\n\n\n<li>Demonstrates excellent blood compatibility.<br>Platelet inactive, Complement inactive, Nonhemolytic <br>Prevents blood coagulation over extended periods.<\/li>\n\n\n\n<li>Suppresses protein adsorption.<\/li>\n\n\n\n<li>Inhibits the adhesion of microorganisms (bacteria).<\/li>\n\n\n\n<li>Cell adhesion can be controlled by selecting appropriate formulations.<br>Enables both antithrombogenicity and cell adhesion to be achieved simultaneously.<\/li>\n<\/ol>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"anc03\">Examples of Applications<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Coating agent for medical devices<\/li>\n\n\n\n<li>Cell culture substrate<\/li>\n\n\n\n<li>Cell tissue scaffolding material<\/li>\n\n\n\n<li>Cancer diagnostic kit<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"anc04\">Key Features and Properties Data<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>&#8211; High content of intermediate water and a low proportion of non-freezing water<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"513\" height=\"441\" src=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image.png\" alt=\"\" class=\"wp-image-20139\" srcset=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image.png 513w, https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-300x258.png 300w\" sizes=\"(max-width: 513px) 100vw, 513px\" \/><\/figure>\n\n\n\n<p>RX-6-GH-30 has as much intermediate water as PVP. The ratio of non-freezing water to intermediate water is as small as PMEA.<br>Based on the intermediate water analysis, GH-30 is presumed to have superior biocompatibility compared to PVP and PMEA, which are already in practical use as antithrombotic polymers.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">&#8211; <strong>Excellent\u3000Antithrombogenic property<\/strong><\/h3>\n\n\n\n<p>It inhibits platelet adhesion and prevents platelet activation.<br>\u3010Platelet-rich plasma\uff0fLeave for 1hr\u3011<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"633\" height=\"482\" src=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-1.png\" alt=\"\" class=\"wp-image-20140\" srcset=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-1.png 633w, https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-1-300x228.png 300w\" sizes=\"(max-width: 633px) 100vw, 633px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">&#8211; <strong>Suppresses protein adsorption<\/strong><\/h3>\n\n\n\n<p>\u2460 GH-30 inhibits the adsorption of blood proteins.<br>\u2461 GH-30 inhibits the adsorption of various proteins with different surface charges.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"333\" src=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-2-1024x333.png\" alt=\"\" class=\"wp-image-20141\" srcset=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-2-1024x333.png 1024w, https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-2-300x98.png 300w, https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-2-768x250.png 768w, https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-2.png 1040w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>&#8211; Inhibits the adhesion of microorganisms (bacteria)<\/strong><\/h3>\n\n\n\n<p>It suppresses the adhesion of bacteria that cause food poisoning and tooth decay, as well as biofilm-forming bacteria.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"602\" height=\"384\" src=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-3.png\" alt=\"\" class=\"wp-image-20142\" srcset=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-3.png 602w, https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-3-300x191.png 300w\" sizes=\"(max-width: 602px) 100vw, 602px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">&#8211; <strong>Lubricant Coating<\/strong><\/h3>\n\n\n\n<p>GH crosslinked coating film has a certain degree of water resistance and forms a surface with excellent lubricity in wet conditions.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-1 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"575\" height=\"418\" src=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/Lubricant-coating.png\" alt=\"\" class=\"wp-image-20144\" srcset=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/Lubricant-coating.png 575w, https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/Lubricant-coating-300x218.png 300w\" sizes=\"(max-width: 575px) 100vw, 575px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\">\n<p>Load 400gf, Speed 1000mm\/min<br>Sus plate(1\u339d\u00d71cm)<br>Distance 20mm\u3000\u3000\u3000<br>In water 100cycle<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"184\" height=\"139\" src=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-4.png\" alt=\"\" class=\"wp-image-20145\" style=\"width:130px;height:auto\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" src=\"https:\/\/www.shokubai.co.jp\/ja\/wpdir\/wp-content\/uploads\/2026\/03\/\u88c5\u7f6e.png\" alt=\"\" class=\"wp-image-26089\" style=\"width:221px;height:auto\"\/><figcaption class=\"wp-element-caption\">Evaluation device\uff1a<br>TL201Tt (Trinity-Lab. Inc.) <br>https:\/\/trinity-lab.com\/<\/figcaption><\/figure>\n\n\n\n<p><br><\/p>\n<\/div>\n<\/div>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" src=\"https:\/\/www.shokubai.co.jp\/ja\/wpdir\/wp-content\/uploads\/2026\/03\/image-5.png\" alt=\"\" class=\"wp-image-26090\" style=\"width:663px;height:auto\"\/><figcaption class=\"wp-element-caption\">Load 450gf, Speed 1000mm\/min, Silicone rubber(1\u339d\u00d71cm), Distance 20mm, In water 100cycle<\/figcaption><\/figure>\n\n\n\n<p>GH coating has excellent durability, maintaining low friction resistance even after 100 cycles of sliding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"anc05\">Disclaimer<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>With respect to this development product, Nippon Shokubai makes no warranties of any kind, including, without limitation, any warranty that its use does not infringe the intellectual property rights of any third party, and shall not be liable for any issues or damages arising from such use.<\/li>\n\n\n\n<li>As this product is a development product, please independently assess its compliance with applicable laws, regulations, standards, and guidelines related to its intended use.<\/li>\n\n\n\n<li>This page presents examples of material property data and research and evaluation results, and does not guarantee the performance, efficacy, or safety of this material or this development product.<\/li>\n\n\n\n<li>This material is not a pharmaceutical or medical device and is not intended to be sold for use in specific medical applications.<\/li>\n\n\n\n<li>The contents (and specifications) described on this page are subject to change without prior notice.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Basic Information Features and Properties Examples of Applications Key Features and Properties Data &#8211; Hi [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"cat_products":[328],"class_list":["post-2238","products","type-products","status-publish","format-standard","hentry","cat_products-uses_08_01_05"],"aioseo_notices":[],"acf":{"products_common_name":"","products_main_uses":"","products_same_series":[{"ID":2214,"post_author":"1","post_date":"2022-07-26 17:42:10","post_date_gmt":"2022-07-26 08:42:10","post_content":"<!-- wp:my-gutenberg\/my-block00 -->\n<div class=\"wp-block-my-gutenberg-my-block00 m_ancNav\"><ul class=\"anc_content\"><li><a href=\"#anc01\">Basic Information<\/a><\/li><li><a href=\"#anc03\">Mechanism of Biocompatibility<\/a><\/li><\/ul><\/div>\n<!-- \/wp:my-gutenberg\/my-block00 -->\n\n<!-- wp:heading -->\n<h2 class=\"wp-block-heading\" id=\"anc01\">Basic Information\n<\/h2>\n<!-- \/wp:heading -->\n\n<!-- wp:paragraph -->\n<p>Intermediate Water Polymer is a hydrophilic, biocompatible polymer developed by Nippon Shokubai through joint research with Professor Masaru Tanaka of the Institute for Materials Chemistry and Engineering (IMEC), Kyushu University.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:heading {\"level\":3} -->\n<h3 class=\"wp-block-heading\">What is Intermediate Water Polymer?<\/h3>\n<!-- \/wp:heading -->\n\n<!-- wp:paragraph -->\n<p>Professor Masaru Tanaka\u2019s research revealed that polymer materials with excellent biocompatibility share a common characteristic : they contain intermediate water.*<br>Intermediate water polymers are polymer materials designed and developed to contain a large amount of intermediate water.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:image {\"lightbox\":{\"enabled\":false},\"id\":2704,\"sizeSlug\":\"full\",\"linkDestination\":\"custom\"} -->\n<figure class=\"wp-block-image size-full\"><a href=\"https:\/\/www.soft-material.jp\/home-e\" target=\"_blank\" rel=\"noreferrer noopener\"><img src=\"\/en\/wordpress\/wp-content\/uploads\/2022\/07\/img_materials10_001.png\" alt=\"\" class=\"wp-image-2704\"\/><\/a><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:paragraph -->\n<p><a href=\"https:\/\/www.soft-material.jp\/home-e\" target=\"_blank\" rel=\"noopener\" title=\"\">Website of the Tanaka Lab., Institute for Materials Chemistry and Engineering (IMCE), Kyushu University<\/a><\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph {\"style\":{\"typography\":{\"fontSize\":\"12px\"},\"color\":{\"text\":\"#6c7872\"}}} -->\n<p class=\"has-text-color\" style=\"color:#6c7872;font-size:12px\">* Intermediate Water<br>When polymer materials are hydrated with water, the hydrated water takes on various states through its interaction with the polymers. These states are roughly grouped into three types depending on the degree of interaction: free water, intermediate water, and non-freezing water. Intermediate water is the middle state between free water and non-freezing water, and is water that gently interacts with polymers.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:flexible-table-block\/table -->\n<figure class=\"wp-block-flexible-table-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><th style=\"width:12%\"><\/th><th style=\"width:22%\">Interaction with Polymers<\/th><th style=\"width:15%\">Freezing Point<\/th><th><\/th><\/tr><tr><th>Free Water<\/th><td>Weak<\/td><td>0\u2103<\/td><td>Freezes and melts at 0\u00b0C, just like ordinary water.<\/td><\/tr><tr><th>Intermediate Water<\/th><td>Moderate<\/td><td>&lt; 0\u00b0C<\/td><td>Gently interacts with polymer materials, and freezes and melts at temperatures under 0\u00b0C.<\/td><\/tr><tr><th>Non-freezing Water<\/th><td>Strong<\/td><td>Not detected<\/td><td>Does not freeze even at (minus) -150\u00b0C.<\/td><\/tr><\/tbody><\/table><\/figure>\n<!-- \/wp:flexible-table-block\/table -->\n\n<!-- wp:paragraph -->\n<p><\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:heading -->\n<h2 class=\"wp-block-heading\" id=\"anc03\">Mechanism of Biocompatibility<\/h2>\n<!-- \/wp:heading -->\n\n<!-- wp:paragraph -->\n<p>Biological foreign-body and rejection responses begin when cells recognize a material as foreign. Cells perceive their external environment primarily through proteins.<br>Because intermediate water is loosely structured, it remains on the polymer surface for an extended period and is believed to function as a cushion layer that inhibits direct contact between proteins or cells and the polymer surface. As a result, polymers rich in intermediate water are considered less likely to be recognized as foreign by the body.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>On the other hand, reports (*) indicate that when proteins come into contact with non-freezing water formed on polymer surfaces, the proteins tend to undergo dehydration and denaturation. From the perspective of biocompatibility, non-freezing water is therefore considered undesirable.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>Nippon Shokubai\u2019s Intermediate Water Polymer is characterized by a high content of intermediate water and a low amount of non-freezing water.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph {\"style\":{\"typography\":{\"fontSize\":\"12px\"},\"color\":{\"text\":\"#6c7872\"}}} -->\n<p class=\"has-text-color\" style=\"color:#6c7872;font-size:12px\">* Journal of Biomaterials Science, Polymer Edition, Vol.3, p.127 (1992)<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:image {\"id\":8934,\"sizeSlug\":\"large\",\"linkDestination\":\"none\"} -->\n<figure class=\"wp-block-image size-large\"><img src=\"\/en\/wordpress\/wp-content\/uploads\/2022\/11\/img_materials10_002-1024x430.png\" alt=\"Illustration  of Functions \" class=\"wp-image-8934\"\/><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:paragraph -->\n<p><\/p>\n<!-- \/wp:paragraph -->","post_title":"Intermediate Water Polymer","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"interwater","to_ping":"","pinged":"","post_modified":"2026-02-20 09:35:10","post_modified_gmt":"2026-02-20 00:35:10","post_content_filtered":"","post_parent":0,"guid":"http:\/\/shokubai.mediawars.ne.jp\/ja\/?post_type=products&#038;p=2214","menu_order":0,"post_type":"products","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":2238,"post_author":"1","post_date":"2022-07-26 18:02:08","post_date_gmt":"2022-07-26 09:02:08","post_content":"<!-- wp:my-gutenberg\/my-block00 -->\n<div class=\"wp-block-my-gutenberg-my-block00 m_ancNav\"><ul class=\"anc_content\"><li><a href=\"#anc01\">Basic Information<\/a><\/li><li><a href=\"#anc02\">Features and Properties<\/a><\/li><li><a href=\"#anc03\">Examples of Applications<\/a><\/li><li><a href=\"#anc04\">Key Features and Properties<\/a><\/li><li><a href=\"#anc05\" title=\"\">Disclaimer<\/a><\/li><\/ul><\/div>\n<!-- \/wp:my-gutenberg\/my-block00 -->\n\n<!-- wp:heading -->\n<h2 class=\"wp-block-heading\" id=\"anc01\">Basic Information<\/h2>\n<!-- \/wp:heading -->\n\n<!-- wp:flexible-table-block\/table -->\n<figure class=\"wp-block-flexible-table-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th><\/th><th colspan=\"2\"><strong>RX-6-GH-30<\/strong>\uff08in development\uff09<\/th><\/tr><\/thead><tbody><tr><th>Appearance<\/th><td colspan=\"2\">Colorless and transparent<\/td><\/tr><tr><th>Solid<\/th><td colspan=\"2\">30 \uff05\uff08aqueous\uff09<\/td><\/tr><tr><th>Viscosity<\/th><td colspan=\"2\">1000 \uff4dPas<\/td><\/tr><tr><th>Toxicity and Safety<\/th><td colspan=\"2\">Ames Test:\u3000Negative\uff085000\u03bcg\/plate\uff09 <br>Cytotoxicity: None (IC<sub>50 <\/sub>\uff1e\uff15000\u03bcg\/mL) <br>Skin Sensitization: Negative (Test concentration: 100% (v\/v); Positive rate: 0%)<\/td><\/tr><tr><th rowspan=\"6\">Wet adhesion (after curing)<\/th><td>polyester<\/td><td>excellent<\/td><\/tr><tr><td>nylon<\/td><td>good<\/td><\/tr><tr><td>vinyl cloride<\/td><td>excellent<\/td><\/tr><tr><td>sus\uff08304\uff09<\/td><td>poor<\/td><\/tr><tr><td>Al<\/td><td>poor<\/td><\/tr><tr><td>glass<\/td><td>good<\/td><\/tr><\/tbody><\/table><\/figure>\n<!-- \/wp:flexible-table-block\/table -->\n\n<!-- wp:heading -->\n<h2 class=\"wp-block-heading\" id=\"anc02\">Features and Properties<\/h2>\n<!-- \/wp:heading -->\n\n<!-- wp:list {\"ordered\":true,\"start\":1} -->\n<ol start=\"1\" class=\"wp-block-list\"><!-- wp:list-item -->\n<li>Exhibits excellent biocompatibility due to a high content of intermediate water and a low proportion of non-freezing water.<\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li>Forms coatings that combine hydrophilicity and water resistance when used in combination with crosslinking agents<\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li>Demonstrates excellent blood compatibility.<br>Platelet inactive, Complement inactive, Nonhemolytic <br>Prevents blood coagulation over extended periods.<\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li>Suppresses protein adsorption.<\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li>Inhibits the adhesion of microorganisms (bacteria).<\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li>Cell adhesion can be controlled by selecting appropriate formulations.<br>Enables both antithrombogenicity and cell adhesion to be achieved simultaneously.<\/li>\n<!-- \/wp:list-item --><\/ol>\n<!-- \/wp:list -->\n\n<!-- wp:heading -->\n<h2 class=\"wp-block-heading\" id=\"anc03\">Examples of Applications<\/h2>\n<!-- \/wp:heading -->\n\n<!-- wp:list -->\n<ul class=\"wp-block-list\"><!-- wp:list-item -->\n<li>Coating agent for medical devices<\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li>Cell culture substrate<\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li>Cell tissue scaffolding material<\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li>Cancer diagnostic kit<\/li>\n<!-- \/wp:list-item --><\/ul>\n<!-- \/wp:list -->\n\n<!-- wp:heading -->\n<h2 class=\"wp-block-heading\" id=\"anc04\">Key Features and Properties Data<\/h2>\n<!-- \/wp:heading -->\n\n<!-- wp:heading {\"level\":3} -->\n<h3 class=\"wp-block-heading\"><strong>- High content of intermediate water and a low proportion of non-freezing water<\/strong><\/h3>\n<!-- \/wp:heading -->\n\n<!-- wp:image {\"id\":20139,\"sizeSlug\":\"full\",\"linkDestination\":\"none\"} -->\n<figure class=\"wp-block-image size-full\"><img src=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image.png\" alt=\"\" class=\"wp-image-20139\"\/><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:paragraph -->\n<p>RX-6-GH-30 has as much intermediate water as PVP. The ratio of non-freezing water to intermediate water is as small as PMEA.<br>Based on the intermediate water analysis, GH-30 is presumed to have superior biocompatibility compared to PVP and PMEA, which are already in practical use as antithrombotic polymers.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:heading {\"level\":3} -->\n<h3 class=\"wp-block-heading\">- <strong>Excellent\u3000Antithrombogenic property<\/strong><\/h3>\n<!-- \/wp:heading -->\n\n<!-- wp:paragraph -->\n<p>It inhibits platelet adhesion and prevents platelet activation.<br>\u3010Platelet-rich plasma\uff0fLeave for 1hr\u3011<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:image {\"id\":20140,\"sizeSlug\":\"full\",\"linkDestination\":\"none\"} -->\n<figure class=\"wp-block-image size-full\"><img src=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-1.png\" alt=\"\" class=\"wp-image-20140\"\/><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:heading {\"level\":3} -->\n<h3 class=\"wp-block-heading\">- <strong>Suppresses protein adsorption<\/strong><\/h3>\n<!-- \/wp:heading -->\n\n<!-- wp:paragraph -->\n<p>\u2460 GH-30 inhibits the adsorption of blood proteins.<br>\u2461 GH-30 inhibits the adsorption of various proteins with different surface charges.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:image {\"id\":20141,\"sizeSlug\":\"large\",\"linkDestination\":\"none\"} -->\n<figure class=\"wp-block-image size-large\"><img src=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-2-1024x333.png\" alt=\"\" class=\"wp-image-20141\"\/><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:heading {\"level\":3} -->\n<h3 class=\"wp-block-heading\"><strong>- Inhibits the adhesion of microorganisms (bacteria)<\/strong><\/h3>\n<!-- \/wp:heading -->\n\n<!-- wp:paragraph -->\n<p>It suppresses the adhesion of bacteria that cause food poisoning and tooth decay, as well as biofilm-forming bacteria.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:image {\"id\":20142,\"sizeSlug\":\"full\",\"linkDestination\":\"none\"} -->\n<figure class=\"wp-block-image size-full\"><img src=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-3.png\" alt=\"\" class=\"wp-image-20142\"\/><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:heading {\"level\":3} -->\n<h3 class=\"wp-block-heading\">- <strong>Lubricant Coating<\/strong><\/h3>\n<!-- \/wp:heading -->\n\n<!-- wp:paragraph -->\n<p>GH crosslinked coating film has a certain degree of water resistance and forms a surface with excellent lubricity in wet conditions.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:columns -->\n<div class=\"wp-block-columns\"><!-- wp:column {\"width\":\"66.66%\"} -->\n<div class=\"wp-block-column\" style=\"flex-basis:66.66%\"><!-- wp:image {\"id\":20144,\"sizeSlug\":\"full\",\"linkDestination\":\"none\"} -->\n<figure class=\"wp-block-image size-full\"><img src=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/Lubricant-coating.png\" alt=\"\" class=\"wp-image-20144\"\/><\/figure>\n<!-- \/wp:image --><\/div>\n<!-- \/wp:column -->\n\n<!-- wp:column {\"width\":\"33.33%\"} -->\n<div class=\"wp-block-column\" style=\"flex-basis:33.33%\"><!-- wp:paragraph -->\n<p>Load 400gf, Speed 1000mm\/min<br>Sus plate(1\u339d\u00d71cm)<br>Distance 20mm\u3000\u3000\u3000<br>In water 100cycle<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:image {\"id\":20145,\"width\":\"130px\",\"height\":\"auto\",\"sizeSlug\":\"full\",\"linkDestination\":\"none\"} -->\n<figure class=\"wp-block-image size-full is-resized\"><img src=\"https:\/\/www.shokubai.co.jp\/en\/wordpress\/wp-content\/uploads\/2026\/04\/image-4.png\" alt=\"\" class=\"wp-image-20145\" style=\"width:130px;height:auto\"\/><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:image {\"id\":26089,\"width\":\"221px\",\"height\":\"auto\",\"sizeSlug\":\"full\",\"linkDestination\":\"none\"} -->\n<figure class=\"wp-block-image size-full is-resized\"><img src=\"https:\/\/www.shokubai.co.jp\/ja\/wpdir\/wp-content\/uploads\/2026\/03\/\u88c5\u7f6e.png\" alt=\"\" class=\"wp-image-26089\" style=\"width:221px;height:auto\"\/><figcaption class=\"wp-element-caption\">Evaluation device\uff1a<br>TL201Tt (Trinity-Lab. Inc.) <br>https:\/\/trinity-lab.com\/<\/figcaption><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:paragraph -->\n<p><br><\/p>\n<!-- \/wp:paragraph --><\/div>\n<!-- \/wp:column --><\/div>\n<!-- \/wp:columns -->\n\n<!-- wp:image {\"id\":26090,\"width\":\"663px\",\"height\":\"auto\",\"sizeSlug\":\"full\",\"linkDestination\":\"none\"} -->\n<figure class=\"wp-block-image size-full is-resized\"><img src=\"https:\/\/www.shokubai.co.jp\/ja\/wpdir\/wp-content\/uploads\/2026\/03\/image-5.png\" alt=\"\" class=\"wp-image-26090\" style=\"width:663px;height:auto\"\/><figcaption class=\"wp-element-caption\">Load 450gf, Speed 1000mm\/min, Silicone rubber(1\u339d\u00d71cm), Distance 20mm, In water 100cycle<\/figcaption><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:paragraph -->\n<p>GH coating has excellent durability, maintaining low friction resistance even after 100 cycles of sliding.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:heading -->\n<h2 class=\"wp-block-heading\" id=\"anc05\">Disclaimer<\/h2>\n<!-- \/wp:heading -->\n\n<!-- wp:list -->\n<ul class=\"wp-block-list\"><!-- wp:list-item -->\n<li>With respect to this development product, Nippon Shokubai makes no warranties of any kind, including, without limitation, any warranty that its use does not infringe the intellectual property rights of any third party, and shall not be liable for any issues or damages arising from such use.<\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li>As this product is a development product, please independently assess its compliance with applicable laws, regulations, standards, and guidelines related to its intended use.<\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li>This page presents examples of material property data and research and evaluation results, and does not guarantee the performance, efficacy, or safety of this material or this development product.<\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li>This material is not a pharmaceutical or medical device and is not intended to be sold for use in specific medical applications.<\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li>The contents (and specifications) described on this page are subject to change without prior notice.<\/li>\n<!-- \/wp:list-item --><\/ul>\n<!-- \/wp:list -->","post_title":"Biocompatible Polymer - Nippon Shokubai's Intermediate Water Polymer","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"biocompatible-polymer","to_ping":"","pinged":"","post_modified":"2026-04-17 14:37:52","post_modified_gmt":"2026-04-17 05:37:52","post_content_filtered":"","post_parent":0,"guid":"http:\/\/shokubai.mediawars.ne.jp\/ja\/?post_type=products&#038;p=2238","menu_order":0,"post_type":"products","post_mime_type":"","comment_count":"0","filter":"raw"}],"products_same_uses":"","is_dev_products":true,"memo":"\u4fdd\u5b58\u3067\u304d\u306a\u30442238\u3000\r\n\u30a4\u30f3\u30dd\u30fc\u30c8\u3067\u5bfe\u5fdc\u3002\r\n\u4e00\u90e8\u65e5\u672c\u8a9e\r\n\u753b\u50cf\u65e5\u672c\u8a9e\u3042\u308a\u3000\u4e0a\u7530","show_hreflang":["ja"]},"_links":{"self":[{"href":"https:\/\/www.shokubai.co.jp\/en\/wp-json\/wp\/v2\/products\/2238"}],"collection":[{"href":"https:\/\/www.shokubai.co.jp\/en\/wp-json\/wp\/v2\/products"}],"about":[{"href":"https:\/\/www.shokubai.co.jp\/en\/wp-json\/wp\/v2\/types\/products"}],"author":[{"embeddable":true,"href":"https:\/\/www.shokubai.co.jp\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":24,"href":"https:\/\/www.shokubai.co.jp\/en\/wp-json\/wp\/v2\/products\/2238\/revisions"}],"predecessor-version":[{"id":20349,"href":"https:\/\/www.shokubai.co.jp\/en\/wp-json\/wp\/v2\/products\/2238\/revisions\/20349"}],"wp:attachment":[{"href":"https:\/\/www.shokubai.co.jp\/en\/wp-json\/wp\/v2\/media?parent=2238"}],"wp:term":[{"taxonomy":"cat_products","embeddable":true,"href":"https:\/\/www.shokubai.co.jp\/en\/wp-json\/wp\/v2\/cat_products?post=2238"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}